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Salary & Cost of Living in South San Francisco, CA

South San Francisco, CA: $66,203 median salary, cost of living index 156.4, $16.00/hr minimum wage. Calculate your take-home pay with our free paycheck calculator.

Median Salary

$66,203

$32/hr

Cost of Living

156.4

US avg = 100

Minimum Wage

$16.00

per hour

Unemployment

4.6%

rate

South San Francisco, CA Overview

Population

67,789

Median Salary

$66,203

Average Salary

$74,147

Avg Commute

20 min

Median Home Price

$851,000

Median Rent

$3,438/mo

Job Growth

+0.8%

Sales Tax

7.25%

South San Francisco is located in California with a population of 67,789. The median household salary is $66,203 per year ($32/hour), which is $6,819 above the national median of $59,384. The average commute time is 20 minutes, and the city has a job growth rate of +0.8%.

South San Francisco Paycheck Calculator

Enter your annual salary to see your estimated take-home pay in South San Francisco, CA, after federal, state, and local taxes.

Estimated Annual Take-Home Pay

$48,803

$4,066.91/month · $1,877.04/biweekly · Effective Rate: 26.3%

Gross Pay

$66,203

Federal Tax

-$6,179

State Tax

-$6,157

Local Tax

$0

FICA

-$5,065

Net Pay

$48,803

Pay Breakdown

Net 73.7%
Federal
State
FICA
Take-Home Federal State FICA
ItemMonthlyAnnual
Gross Salary$5,516.92$66,203.00
Federal Income Tax-$514.89-$6,178.66
California State Tax (9.3%)-$513.07-$6,156.88
Social Security (6.2%)-$342.05-$4,104.59
Medicare (1.45%)-$80.00-$959.94
Net Take-Home Pay$4,066.91$48,802.93

Salary Comparison: South San Francisco vs Other Cities

See how South San Francisco's median salary and cost of living compare to the national average and similar cities.

CityMedian SalaryCOL IndexAdj. Salary
South San Francisco, CA$66,203156.4$42,329
National Average$59,384100$59,384
Redondo Beach, CA$66,202154.5$42,849
Milford Mill, MD$66,200112.8$58,688
Encinitas, CA$66,193155.5$42,568
Ewing, NJ$66,215126$52,552

Adjusted salary reflects purchasing power when cost of living is factored in. A higher adjusted salary means your money goes further.

Cost of Living in South San Francisco

South San Francisco's cost of living index is 156.4 (national average = 100). Living in South San Francisco is 56.400000000000006% more expensive than the national average.

Median Home Price

$851,000

Median Monthly Rent

$3,438

Annual Rent Cost

$41,256

Your Salary's Purchasing Power

Your $48,803 annual take-home pay in South San Francisco has the purchasing power of approximately $31,204 in an average-cost US area. You would need to earn $103,541 in South San Francisco to match a $66,203 salary in an average-cost city.

Top Industries in South San Francisco

South San Francisco's economy is driven by these key industries. Workers in top industries often earn significantly above the median salary of $66,203.

1Technology
2Entertainment
3Agriculture
Job Growth: +0.8%Unemployment: 4.6%

Salary Tips for South San Francisco Workers

  • Negotiate for cost of living. South San Francisco has a cost of living 56.400000000000006% above the national average. When negotiating salary, factor in the higher housing and living costs to ensure your real purchasing power stays competitive.
  • Maximize pre-tax deductions. With a 9.3% state income tax rate, maximizing 401(k) contributions (up to $23,500 in 2026) and HSA contributions can significantly reduce both your federal and state tax burden.
  • Research top industries. South San Francisco's top industries include Technology, Entertainment, Agriculture. Targeting roles in these sectors can help you earn above the $66,203 median salary.
  • Review your W-4 withholding. If you regularly receive large tax refunds, adjust your W-4 to increase your per-paycheck take-home pay instead of giving the government an interest-free loan.

Explore Salaries Across the US

Compare salary data and cost of living for hundreds of US cities. Find out where your paycheck goes the furthest.

Frequently Asked Questions

What is the median salary in South San Francisco, CA?

The median salary in South San Francisco, CA is $66,203 per year, or $32 per hour. The average salary is $74,147. This is $6,819 above the national median of $59,384.

What is the cost of living in South San Francisco, CA?

South San Francisco's cost of living index is 156.4 (national average = 100), meaning it is 56.400000000000006% more expensive compared to the national average. The median home price is $851,000 and the median monthly rent is $3,438.

What are the best industries in South San Francisco?

The top industries in South San Francisco, CA include Technology, Entertainment, Agriculture. The city has a job growth rate of 0.8% and an unemployment rate of 4.6%. Workers in these industries often earn above the city's median salary of $66,203.

How does South San Francisco's salary compare to other cities?

South San Francisco's median salary of $66,203 is 11.5% above the national median of $59,384. However, when adjusted for cost of living (index: 156.4), the real purchasing power is approximately $42,329.

What is the minimum wage in South San Francisco, CA?

The minimum wage in South San Francisco, CA is $16.00 per hour. This equals approximately $33,280 per year for a full-time worker (40 hours/week). This is $8.75 above the federal minimum wage of $7.25/hour.