Biostatistician Salary in Chicago, IL — 2026
Biostatistician salary data for Chicago, IL — adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.
The median Biostatistician salary in Chicago, IL is $104,860 per year ($8,738/month, $50/hr). This reflects the local cost of living index of 107, which is 7% above the national average.
Biostatistician Take-Home Pay in Chicago
Tax Breakdown (Median Salary)
| Gross Annual | $104,860 |
| Federal Tax | -$14,239 |
| State Tax (5.0%) | -$5,191 |
| FICA (SS + Medicare) | -$8,022 |
| Annual Take-Home | $77,408 |
| Monthly Take-Home | $6,451 |
Living Cost Comparison
Biostatistician Requirements
Key Skills
Chicago Job Market Overview
Chicago, Illinois has a population of 2,696,555 and an unemployment rate of 4.2%. The top industries are Finance, Technology, Healthcare. The local job growth rate is 1.5%, and the average commute time is 35 minutes.
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Salary Percentile Breakdown — Biostatistician in Chicago
Based on the cost-of-living-adjusted distribution for Biostatistician in Chicago, IL, here's how earnings break down across the workforce:
| Percentile | Annual Salary | Hourly Equivalent | Career Stage |
|---|---|---|---|
| 10th (lowest) | $67,410 | $32/hr | Entry-level, < 1 yr exp. |
| 25th | $86,135 | $41/hr | Junior, 1-3 yrs exp. |
| 50th (median) | $104,860 | $50/hr | Mid-career, 2-4 years |
| 75th | $153,010 | $74/hr | Senior, 5-10 yrs exp. |
| 90th (top) | $190,460 | $92/hr | Lead/Principal, 10+ yrs |
Percentiles estimated using a log-normal salary distribution model calibrated to Biostatistician compensation data. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in Chicago's Finance sector.
5-Year Salary Trajectory
Biostatistician salaries in Chicago have grown approximately 18.0% over the past 5 years, outpacing local CPI inflation in many cases. Here's the historical and projected trajectory:
Year-over-year, an average Biostatistician can expect a 14.6% annual increase moving from entry to senior level over 6 years in Chicago. Negotiation, certifications (PStat, ASA Certification), and changing employers strategically can accelerate this trajectory.
Chicago vs National Average
The national median Biostatistician salary is $98,000. In Chicago, the cost-of-living-adjusted median of $104,860 is 7.0% above the national figure. This reflects Chicago's cost of living index of 107 (higher than the national average of 100).
For Biostatisticians, this means: rent typically consumes 27.1% of take-home pay (households spending >30% are considered affordable), and a median home in Chicago costs about 4.1× annual take-home. Homeownership is relatively attainable on this salary in Chicago.
Industry Context: Finance in Chicago
Chicago's economy is anchored by Finance, Technology, Healthcare, with 2,696,555 residents and 4.2% unemployment as of 2026. Biostatisticians working in the Finance sector typically earn at or above the local median due to industry-specific demand. The state's overall job growth rate is 1.5%, and Biostatistician occupations specifically are projected to grow 30.0% nationally through 2034 (BLS Occupational Outlook Handbook).
Methodology & Data Sources
How we calculate Biostatistician salaries in Chicago, IL:
- Base salary model starts with Salario occupation data and public wage references, including BLS OEWS and O*NET when a direct or related occupational crosswalk is available. For niche titles, we do not treat a broader SOC family as an exact job-title wage.
- Cost-of-living adjustment applied using the Chicago index of 107 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs checked separately.
- Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rather than claimed as exact employer payroll data.
- Take-home pay calculated using 2026 federal tax brackets (10%-37%), IL state income tax of 5.0%, and FICA (Social Security 6.2% + Medicare 1.45%).
- Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.
Authoritative data sources:
- BLS Occupational Employment and Wage Statistics — national and metro-area salary data
- O*NET OnLine — occupation tasks, alternate job titles, skills, and SOC crosswalks
- BLS Occupational Outlook Handbook — occupation outlook where a matching profile is available
- BLS Consumer Price Index (CPI-U) — regional inflation and cost-of-living data
- U.S. Census Bureau — Chicago QuickFacts — population and demographic data
- IRS Revenue Procedure 2025-32 summary — 2026 federal tax brackets and standard deductions
- BLS Local Area Unemployment Statistics — Chicago unemployment rate
Last reviewed: 2026. Salary data updated annually as new BLS releases become available. Biostatistician salaries can vary significantly based on employer, sector (Finance vs others in Chicago), specific skill set (SAS, R, Clinical Trials), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.
Frequently Asked Questions
What is the average Biostatistician salary in Chicago, IL?
How much does a Biostatistician take home in Chicago after taxes?
Is Chicago a good city for Biostatisticians?
What skills are needed for a Biostatistician in Chicago?
How does Biostatistician salary in Chicago compare to the national average?
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Frequently Asked Questions
What is the average Biostatistician salary in Chicago, IL?
The median Biostatistician salary in Chicago, IL is $104,860 per year as of 2026. This is adjusted for the local cost of living index of 107. Entry-level Biostatisticians earn around $67,410, while senior-level professionals can earn $153,010 or more.
How much does a Biostatistician take home in Chicago after taxes?
A Biostatistician earning the median salary of $104,860 in Chicago, IL takes home approximately $77,408 per year ($6,451/month) after federal, state, and local taxes. The effective tax rate is 26.2%.
Is Chicago a good city for Biostatisticians?
Chicago, IL has a cost of living index of 107 (above national average). Biostatisticians here earn above the city median. The local unemployment rate is 4.2% and top industries include Finance, Technology, Healthcare.
What skills are needed for a Biostatistician in Chicago?
Key skills for Biostatisticians include SAS, R, Clinical Trials, Survival Analysis, Epidemiology. Typical education requirement is Master's Degree. Valuable certifications include PStat, ASA Certification.
How does Biostatistician salary in Chicago compare to the national average?
The national median Biostatistician salary is $98,000. In Chicago, the adjusted salary is $104,860, which is 7.0% higher than the national average, reflecting the local cost of living.