Clinical Laboratory Scientist Salary in Minneapolis, MN — 2026
Clinical Laboratory Scientist salary data for Minneapolis, MN — adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.
The median Clinical Laboratory Scientist salary in Minneapolis, MN is $59,160 per year ($4,930/month, $28/hr). This reflects the local cost of living index of 102, which is 2% above the national average.
Clinical Laboratory Scientist Take-Home Pay in Minneapolis
Tax Breakdown (Median Salary)
| Gross Annual | $59,160 |
| Federal Tax | -$4,919 |
| State Tax (6.8%) | -$4,023 |
| FICA (SS + Medicare) | -$4,526 |
| Annual Take-Home | $45,692 |
| Monthly Take-Home | $3,808 |
Living Cost Comparison
Clinical Laboratory Scientist Requirements
Key Skills
Minneapolis Job Market Overview
Minneapolis, Minnesota has a population of 429,954 and an unemployment rate of 2.8%. The top industries are Finance, Healthcare, Technology. The local job growth rate is 2.0%, and the average commute time is 25 minutes.
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Salary Percentile Breakdown — Clinical Laboratory Scientist in Minneapolis
Based on the cost-of-living-adjusted distribution for Clinical Laboratory Scientist in Minneapolis, MN, here's how earnings break down across the workforce:
| Percentile | Annual Salary | Hourly Equivalent | Career Stage |
|---|---|---|---|
| 10th (lowest) | $45,900 | $22/hr | Entry-level, < 1 yr exp. |
| 25th | $52,530 | $25/hr | Junior, 1-3 yrs exp. |
| 50th (median) | $59,160 | $28/hr | Mid-career, 1-2 years |
| 75th | $76,500 | $37/hr | Senior, 5-10 yrs exp. |
| 90th (top) | $89,760 | $43/hr | Lead/Principal, 10+ yrs |
Percentiles estimated using a log-normal salary distribution model calibrated to Clinical Laboratory Scientist compensation data. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in Minneapolis's Finance sector.
5-Year Salary Trajectory
Clinical Laboratory Scientist salaries in Minneapolis have grown approximately 8.0% over the past 5 years, outpacing local CPI inflation in many cases. Here's the historical and projected trajectory:
Year-over-year, an average Clinical Laboratory Scientist can expect a 10.8% annual increase moving from entry to senior level over 5 years in Minneapolis. Negotiation, certifications (MLS(ASCP) Certification), and changing employers strategically can accelerate this trajectory.
Minneapolis vs National Average
The national median Clinical Laboratory Scientist salary is $58,000. In Minneapolis, the cost-of-living-adjusted median of $59,160 is 2.0% above the national figure. This reflects Minneapolis's cost of living index of 102 (higher than the national average of 100).
For Clinical Laboratory Scientists, this means: rent typically consumes 36.8% of take-home pay (households spending >30% are considered rent-burdened), and a median home in Minneapolis costs about 7.0× annual take-home. Homeownership in Minneapolis on this salary is challenging — most experts recommend keeping home costs to 3-4× income.
Industry Context: Finance in Minneapolis
Minneapolis's economy is anchored by Finance, Healthcare, Technology, with 429,954 residents and 2.8% unemployment as of 2026. Clinical Laboratory Scientists working in the Finance sector typically earn at or above the local median due to industry-specific demand. The state's overall job growth rate is 2.0%, and Clinical Laboratory Scientist occupations specifically are projected to grow 7.0% nationally through 2034 (BLS Occupational Outlook Handbook).
Methodology & Data Sources
How we calculate Clinical Laboratory Scientist salaries in Minneapolis, MN:
- Base salary model starts with Salario occupation data and public wage references, including BLS OEWS and O*NET when a direct or related occupational crosswalk is available. For niche titles, we do not treat a broader SOC family as an exact job-title wage.
- Cost-of-living adjustment applied using the Minneapolis index of 102 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs checked separately.
- Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rather than claimed as exact employer payroll data.
- Take-home pay calculated using 2026 federal tax brackets (10%-37%), MN state income tax of 6.8%, and FICA (Social Security 6.2% + Medicare 1.45%).
- Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.
Authoritative data sources:
- BLS Occupational Employment and Wage Statistics — national and metro-area salary data
- O*NET OnLine — occupation tasks, alternate job titles, skills, and SOC crosswalks
- BLS Occupational Outlook Handbook — occupation outlook where a matching profile is available
- BLS Consumer Price Index (CPI-U) — regional inflation and cost-of-living data
- U.S. Census Bureau — Minneapolis QuickFacts — population and demographic data
- IRS Revenue Procedure 2025-32 summary — 2026 federal tax brackets and standard deductions
- BLS Local Area Unemployment Statistics — Minneapolis unemployment rate
Last reviewed: 2026. Salary data updated annually as new BLS releases become available. Clinical Laboratory Scientist salaries can vary significantly based on employer, sector (Finance vs others in Minneapolis), specific skill set (Blood Analysis, Microbiology, Chemistry), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.
Frequently Asked Questions
What is the average Clinical Laboratory Scientist salary in Minneapolis, MN?
How much does a Clinical Laboratory Scientist take home in Minneapolis after taxes?
Is Minneapolis a good city for Clinical Laboratory Scientists?
What skills are needed for a Clinical Laboratory Scientist in Minneapolis?
How does Clinical Laboratory Scientist salary in Minneapolis compare to the national average?
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- Amortio: Home Affordability — what home you can buy on this income
Frequently Asked Questions
What is the average Clinical Laboratory Scientist salary in Minneapolis, MN?
The median Clinical Laboratory Scientist salary in Minneapolis, MN is $59,160 per year as of 2026. This is adjusted for the local cost of living index of 102. Entry-level Clinical Laboratory Scientists earn around $45,900, while senior-level professionals can earn $76,500 or more.
How much does a Clinical Laboratory Scientist take home in Minneapolis after taxes?
A Clinical Laboratory Scientist earning the median salary of $59,160 in Minneapolis, MN takes home approximately $45,692 per year ($3,808/month) after federal, state, and local taxes. The effective tax rate is 22.8%.
Is Minneapolis a good city for Clinical Laboratory Scientists?
Minneapolis, MN has a cost of living index of 102 (above national average). Clinical Laboratory Scientists here earn below the city median. The local unemployment rate is 2.8% and top industries include Finance, Healthcare, Technology.
What skills are needed for a Clinical Laboratory Scientist in Minneapolis?
Key skills for Clinical Laboratory Scientists include Blood Analysis, Microbiology, Chemistry, Hematology, Quality Control. Typical education requirement is Bachelor's Degree. Valuable certifications include MLS(ASCP) Certification.
How does Clinical Laboratory Scientist salary in Minneapolis compare to the national average?
The national median Clinical Laboratory Scientist salary is $58,000. In Minneapolis, the adjusted salary is $59,160, which is 2.0% higher than the national average, reflecting the local cost of living.