Medical Assistant Salary in Denver, CO: 2026
Medical Assistant salary data for Denver, CO, adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.
The median Medical Assistant salary in Denver, CO is $49,700 per year ($4,142/month, $23.89/hr). That is the BLS OEWS May 2025 median annual wage for Medical Assistants in the Denver-Aurora-Centennial, CO metropolitan area, which covers Denver. Salario's cost-of-living model (index 118) would have estimated $53,914; the entry, senior and top tiers below are Salario estimates rescaled to the BLS median.
Median: BLS OEWS May 2025, Medical Assistants (SOC 31-9092), Denver-Aurora-Centennial, CO MSA. Entry, senior and top earner are Salario estimates rescaled to the BLS median.
Medical Assistant Take-Home Pay in Denver
Tax Breakdown (Median Salary)
| Gross Annual | $49,700 |
| Federal Tax | -$3,784 |
| State Tax (3.0% eff.) | -$1,478 |
| FICA (SS + Medicare) | -$3,802 |
| Annual Take-Home | $40,636 |
| Monthly Take-Home | $3,386 |
Living Cost Comparison
Medical Assistant Requirements
Key Skills
Denver Job Market Overview
Denver, Colorado has a population of 715,522 and an unemployment rate of 3.0%. The top industries are Technology, Energy, Healthcare. The local job growth rate is 2.5%, and the average commute time is 27minutes. These local figures come from Salario's city dataset; verify current values with BLS Local Area Unemployment Statistics and Census QuickFacts.
Related Healthcare Salaries in Denver
Medical Assistant Salary in Nearby Colorado Cities
Salary Percentile Breakdown: Medical Assistant in Denver
Based on Salario's cost-of-living-adjusted salary tiers for Medical Assistant in Denver, CO, here is an estimated percentile breakdown:
| Percentile | Annual Salary | Hourly Equivalent | Career Stage |
|---|---|---|---|
| 10th (lowest) | $39,500 | $19/hr | Entry-level, < 1 yr exp. |
| 25th | $44,600 | $21/hr | Junior, 1-3 yrs exp. |
| 50th (median) | $49,700 | $24/hr | Mid-career, 0-1 year |
| 75th | $59,900 | $29/hr | Senior, 5-10 yrs exp. |
| 90th (top) | $71,400 | $34/hr | Lead/Principal, 10+ yrs |
P50 is the measured BLS OEWS May 2025 metro median; P10, P25, P75 and P90 are approximations, not measured local percentiles: they map to Salario's entry, senior and top tiers rescaled to the BLS median, with P25 interpolated halfway between entry and median. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in Denver's Technology sector.
5-Year Salary Trajectory
Salario's national dataset models approximately 8.0% salary growth for Medical Assistants over the past 5 years. That national assumption is applied to the Denver estimate below; it is not a measured local trend, and it should be compared with cumulative CPI inflation before treating it as a real-terms gain:
Year-over-year, an average Medical Assistant can expect a 11.0% annual increase moving from entry to senior level over 4 years in Denver. Negotiation, certifications (CMA, RMA), and changing employers strategically can accelerate this trajectory.
Denver vs National Average
The national median Medical Assistant salary is $45,690 (BLS OEWS May 2025, Medical Assistants). In the Denver-Aurora-Centennial, CO metro, the BLS median of $49,700 is 8.8% above the national figure. Denver's cost of living index is 118 (higher than the national average of 100), so the wage premium and the cost premium do not necessarily cancel out.
For Medical Assistants, this means: rent typically consumes 54.6% of take-home pay (households spending >30% are considered rent-burdened), and a median home in Denver costs about 13.5× annual take-home. Homeownership in Denver on this salary is challenging, most experts recommend keeping home costs to 3-4× income.
Industry Context: Technology in Denver
Denver's economy is anchored by Technology, Energy, Healthcare, with 715,522 residents and an unemployment rate of 3.0% in Salario's city dataset. Pay for Medical Assistants can differ by sector, so compare Technology employers with other local employers. The local job growth rate in Salario's city dataset is 2.5%, and Salario's job dataset lists a 14.0% growth outlook for Medical Assistant roles; check the BLS Occupational Outlook Handbook for the official 2024-2034 projection for the closest matching occupation.
Methodology & Data Sources
How we calculate Medical Assistant salaries in Denver, CO:
- Local median is the BLS OEWS May 2025 median annual wage for Medical Assistants (SOC 31-9092) in the Denver-Aurora-Centennial, CO metropolitan statistical area, retrieved from the BLS Public Data API on September 17, 2026. BLS reports by metro area, so this is a regional figure, not a Denver-only wage.
- Cost-of-living adjustment is shown only for comparison ($53,914 modeled) using the Denver index of 118 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs stored separately in Salario's city dataset.
- Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rescaled to the BLS metro median rather than claimed as exact employer payroll data.
- Take-home pay calculated using 2026 federal tax brackets (10%-37%), CO 2026 state income tax brackets after the standard deduction (top rate 4.4%), and FICA (Social Security 6.2% + Medicare 1.45%).
- Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.
Authoritative data sources:
- BLS Occupational Employment and Wage Statistics, national and metro-area salary data
- O*NET OnLine, occupation tasks, alternate job titles, skills, and SOC crosswalks
- BLS Occupational Outlook Handbook, occupation outlook where a matching profile is available
- BLS Consumer Price Index (CPI-U), regional inflation data (CPI measures price changes, not city-to-city price levels)
- U.S. Census Bureau, Denver QuickFacts, population and demographic data
- IRS Revenue Procedure 2025-32 summary, 2026 federal tax brackets and standard deductions
- BLS Local Area Unemployment Statistics, official local unemployment rates to verify the Denver figure above
Last reviewed: 2026. Salario's salary dataset is refreshed periodically, not automatically; check the linked BLS releases for the latest official data. Medical Assistant salaries can vary significantly based on employer, sector (Technology vs others in Denver), specific skill set (Vital Signs, Phlebotomy, EHR), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.
Frequently Asked Questions
What is the average Medical Assistant salary in Denver, CO?
How much does a Medical Assistant take home in Denver after taxes?
Is Denver a good city for Medical Assistants?
What skills are needed for a Medical Assistant in Denver?
How does Medical Assistant salary in Denver compare to the national average?
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Frequently Asked Questions
What is the average Medical Assistant salary in Denver, CO?
The median Medical Assistant salary in Denver, CO is $49,700 per year: the BLS OEWS May 2025 median annual wage for Medical Assistants (SOC 31-9092) in the Denver-Aurora-Centennial, CO metropolitan area. BLS publishes wages by metro area, not by city. The entry-level estimate of around $39,500 and the senior estimate of $59,900 or more are Salario tiers calibrated to that BLS median, not BLS percentiles.
How much does a Medical Assistant take home in Denver after taxes?
A Medical Assistant earning the median salary of $49,700 in Denver, CO takes home approximately $40,636 per year ($3,386/month) after federal, state, and local taxes. The effective tax rate is 18.2%.
Is Denver a good city for Medical Assistants?
Denver, CO has a cost of living index of 118 (above national average). Medical Assistants here earn below the city median. The local unemployment rate is 3.0% and top industries include Technology, Energy, Healthcare.
What skills are needed for a Medical Assistant in Denver?
Key skills for Medical Assistants include Vital Signs, Phlebotomy, EHR, Patient Scheduling, Clinical Procedures. Typical education requirement is Certificate. Valuable certifications include CMA, RMA, BLS.
How does Medical Assistant salary in Denver compare to the national average?
The national median for Medical Assistants is $45,690 (BLS OEWS May 2025). In the Denver-Aurora-Centennial, CO metro, the BLS median is $49,700, which is 8.8% higher than the national figure. For comparison, Salario's cost-of-living model (index 118) would have estimated $53,914.