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Medical Assistant Salary in Fresno, CA — 2026

Medical Assistant salary data for Fresno, CA — adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.

The median Medical Assistant salary in Fresno, CA is $39,000 per year ($3,250/month, $19/hr). This reflects the local cost of living index of 100, which is 0% below the national average.

Entry Level
$31K
$15/hr
Median
$39K
$19/hr
Senior
$47K
$23/hr
Top Earner
$56K
$27/hr

Medical Assistant Take-Home Pay in Fresno

Tax Breakdown (Median Salary)

Gross Annual$39,000
Federal Tax-$2,500
State Tax (9.3%)-$3,627
FICA (SS + Medicare)-$2,984
Annual Take-Home$29,890
Monthly Take-Home$2,491

Living Cost Comparison

Median Rent$1,200/mo
Rent-to-Income Ratio36.9%
Median Home Price$325,000
Cost of Living Index100
City Median Salary$48,500
Medical Assistant vs City Median$-9,500

Medical Assistant Requirements

Education
Certificate
Experience
0-1 year
Job Growth
14.0% (2024-2034)

Key Skills

Vital SignsPhlebotomyEHRPatient SchedulingClinical Procedures

Fresno Job Market Overview

Fresno, California has a population of 542,107 and an unemployment rate of 5.5%. The top industries are Agriculture, Healthcare, Education. The local job growth rate is 1.2%, and the average commute time is 22 minutes.

Salary Percentile Breakdown — Medical Assistant in Fresno

Based on the cost-of-living-adjusted distribution for Medical Assistant in Fresno, CA, here's how earnings break down across the workforce:

PercentileAnnual SalaryHourly EquivalentCareer Stage
10th (lowest)$31,000$15/hrEntry-level, < 1 yr exp.
25th$35,000$17/hrJunior, 1-3 yrs exp.
50th (median)$39,000$19/hrMid-career, 0-1 year
75th$47,000$23/hrSenior, 5-10 yrs exp.
90th (top)$56,000$27/hrLead/Principal, 10+ yrs

Percentiles estimated using a log-normal salary distribution model calibrated to Medical Assistant compensation data. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in Fresno's Agriculture sector.

5-Year Salary Trajectory

Medical Assistant salaries in Fresno have grown approximately 8.0% over the past 5 years, outpacing local CPI inflation in many cases. Here's the historical and projected trajectory:

5 Years Ago
$36,111
Adjusted for Fresno COL
Today (2026)
$39,000
+8.0% vs 5y ago
Projected 2031
$42,120
If growth continues

Year-over-year, an average Medical Assistant can expect a 11.0% annual increase moving from entry to senior level over 4 years in Fresno. Negotiation, certifications (CMA, RMA), and changing employers strategically can accelerate this trajectory.

Fresno vs National Average

The national median Medical Assistant salary is $39,000. In Fresno, the cost-of-living-adjusted median of $39,000 is 0.0% below the national figure. This reflects Fresno's cost of living index of 100 (lower than the national average of 100).

For Medical Assistants, this means: rent typically consumes 48.2% of take-home pay (households spending >30% are considered rent-burdened), and a median home in Fresno costs about 10.9× annual take-home. Homeownership in Fresno on this salary is challenging — most experts recommend keeping home costs to 3-4× income.

Industry Context: Agriculture in Fresno

Fresno's economy is anchored by Agriculture, Healthcare, Education, with 542,107 residents and 5.5% unemployment as of 2026. Medical Assistants working in the Agriculture sector typically earn at or above the local median due to industry-specific demand. The state's overall job growth rate is 1.2%, and Medical Assistant occupations specifically are projected to grow 14.0% nationally through 2034 (BLS Occupational Outlook Handbook).

Methodology & Data Sources

How we calculate Medical Assistant salaries in Fresno, CA:

  1. Base salary model starts with Salario occupation data and public wage references, including BLS OEWS and O*NET when a direct or related occupational crosswalk is available. For niche titles, we do not treat a broader SOC family as an exact job-title wage.
  2. Cost-of-living adjustment applied using the Fresno index of 100 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs checked separately.
  3. Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rather than claimed as exact employer payroll data.
  4. Take-home pay calculated using 2026 federal tax brackets (10%-37%), CA state income tax of 9.3%, and FICA (Social Security 6.2% + Medicare 1.45%).
  5. Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.

Authoritative data sources:

Last reviewed: 2026. Salary data updated annually as new BLS releases become available. Medical Assistant salaries can vary significantly based on employer, sector (Agriculture vs others in Fresno), specific skill set (Vital Signs, Phlebotomy, EHR), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.

Frequently Asked Questions

What is the average Medical Assistant salary in Fresno, CA?
The median Medical Assistant salary in Fresno, CA is $39,000 per year as of 2026. This is adjusted for the local cost of living index of 100. Entry-level Medical Assistants earn around $31,000, while senior-level professionals can earn $47,000 or more.
How much does a Medical Assistant take home in Fresno after taxes?
A Medical Assistant earning the median salary of $39,000 in Fresno, CA takes home approximately $29,890 per year ($2,491/month) after federal, state, and local taxes. The effective tax rate is 23.4%.
Is Fresno a good city for Medical Assistants?
Fresno, CA has a cost of living index of 100 (below national average). Medical Assistants here earn below the city median. The local unemployment rate is 5.5% and top industries include Agriculture, Healthcare, Education.
What skills are needed for a Medical Assistant in Fresno?
Key skills for Medical Assistants include Vital Signs, Phlebotomy, EHR, Patient Scheduling, Clinical Procedures. Typical education requirement is Certificate. Valuable certifications include CMA, RMA, BLS.
How does Medical Assistant salary in Fresno compare to the national average?
The national median Medical Assistant salary is $39,000. In Fresno, the adjusted salary is $39,000, which is 0.0% lower than the national average, reflecting the local cost of living.

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Frequently Asked Questions

What is the average Medical Assistant salary in Fresno, CA?

The median Medical Assistant salary in Fresno, CA is $39,000 per year as of 2026. This is adjusted for the local cost of living index of 100. Entry-level Medical Assistants earn around $31,000, while senior-level professionals can earn $47,000 or more.

How much does a Medical Assistant take home in Fresno after taxes?

A Medical Assistant earning the median salary of $39,000 in Fresno, CA takes home approximately $29,890 per year ($2,491/month) after federal, state, and local taxes. The effective tax rate is 23.4%.

Is Fresno a good city for Medical Assistants?

Fresno, CA has a cost of living index of 100 (below national average). Medical Assistants here earn below the city median. The local unemployment rate is 5.5% and top industries include Agriculture, Healthcare, Education.

What skills are needed for a Medical Assistant in Fresno?

Key skills for Medical Assistants include Vital Signs, Phlebotomy, EHR, Patient Scheduling, Clinical Procedures. Typical education requirement is Certificate. Valuable certifications include CMA, RMA, BLS.

How does Medical Assistant salary in Fresno compare to the national average?

The national median Medical Assistant salary is $39,000. In Fresno, the adjusted salary is $39,000, which is 0.0% lower than the national average, reflecting the local cost of living.