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Physician Assistant Salary in San Antonio, TX — 2026

Physician Assistant salary data for San Antonio, TX — adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.

The median Physician Assistant salary in San Antonio, TX is $108,240 per year ($9,020/month, $52/hr). This reflects the local cost of living index of 88, which is 12% below the national average.

Also known as: PA, Physician Associate, Medical Assistant. Salary data on this page applies to all of these job titles in San Antonio, TX.

Entry Level
$81K
$39/hr
Median
$108K
$52/hr
Senior
$138K
$66/hr
Top Earner
$165K
$79/hr

Physician Assistant Take-Home Pay in San Antonio

Tax Breakdown (Median Salary)

Gross Annual$108,240
Federal Tax-$14,983
State Tax (0.0%)-$0
FICA (SS + Medicare)-$8,280
Annual Take-Home$84,977
Monthly Take-Home$7,081

Living Cost Comparison

Median Rent$1,200/mo
Rent-to-Income Ratio13.3%
Median Home Price$250,000
Cost of Living Index88
City Median Salary$55,000
Physician Assistant vs City Median+$53,240

Physician Assistant Requirements

Education
Master's Degree
Experience
0-2 years
Job Growth
28.0% (2024-2034)

Key Skills

Clinical ExaminationDiagnosisProcedure AssistanceEHRPatient Education

Physician Assistant salary search terms in San Antonio

People comparing Physician Assistant pay in San Antonio, TX may use related job-title wording. Salario keeps the main estimate tied to the Physician Assistant role, then treats the terms below as comparison phrases that should be checked for licensing, employer type, seniority, and role scope.

PAPhysician AssociateMedical Assistant
Comparison pointHow to use it
Primary local answer$108,240 median salary, $80,960-$138,160 modeled range, and $84,977 estimated take-home pay in San Antonio.
Title variantsPA, Physician Associate, Medical Assistant can point to similar searches, but some variants may represent a narrower specialty or a higher/lower seniority band.
Offer comparisonCompare base salary, hourly equivalent, take-home pay, certifications, local cost of living, and whether the job is employee, contractor, public-sector, commission-heavy, or management-level.

San Antonio Job Market Overview

San Antonio, Texas has a population of 1,434,625 and an unemployment rate of 3.5%. The top industries are Military, Healthcare, Tourism. The local job growth rate is 2.2%, and the average commute time is 25 minutes.

Salary Percentile Breakdown — Physician Assistant in San Antonio

Based on the cost-of-living-adjusted distribution for Physician Assistant in San Antonio, TX, here's how earnings break down across the workforce:

PercentileAnnual SalaryHourly EquivalentCareer Stage
10th (lowest)$80,960$39/hrEntry-level, < 1 yr exp.
25th$94,600$45/hrJunior, 1-3 yrs exp.
50th (median)$108,240$52/hrMid-career, 0-2 years
75th$138,160$66/hrSenior, 5-10 yrs exp.
90th (top)$164,560$79/hrLead/Principal, 10+ yrs

Percentiles estimated using a log-normal salary distribution model calibrated to Physician Assistant compensation data. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in San Antonio's Military sector.

5-Year Salary Trajectory

Physician Assistant salaries in San Antonio have grown approximately 15.0% over the past 5 years, outpacing local CPI inflation in many cases. Here's the historical and projected trajectory:

5 Years Ago
$94,122
Adjusted for San Antonio COL
Today (2026)
$108,240
+15.0% vs 5y ago
Projected 2031
$124,476
If growth continues

Year-over-year, an average Physician Assistant can expect a 14.3% annual increase moving from entry to senior level over 4 years in San Antonio. Negotiation, certifications (PANCE, NCCPA Certification), and changing employers strategically can accelerate this trajectory.

San Antonio vs National Average

The national median Physician Assistant salary is $123,000. In San Antonio, the cost-of-living-adjusted median of $108,240 is 12.0% below the national figure. This reflects San Antonio's cost of living index of 88 (lower than the national average of 100).

For Physician Assistants, this means: rent typically consumes 16.9% of take-home pay (households spending >30% are considered affordable), and a median home in San Antonio costs about 2.9× annual take-home. Homeownership is relatively attainable on this salary in San Antonio.

Industry Context: Military in San Antonio

San Antonio's economy is anchored by Military, Healthcare, Tourism, with 1,434,625 residents and 3.5% unemployment as of 2026. Physician Assistants working in the Military sector typically earn at or above the local median due to industry-specific demand. The state's overall job growth rate is 2.2%, and Physician Assistant occupations specifically are projected to grow 28.0% nationally through 2034 (BLS Occupational Outlook Handbook).

Methodology & Data Sources

How we calculate Physician Assistant salaries in San Antonio, TX:

  1. Base salary model starts with Salario occupation data and public wage references, including BLS OEWS and O*NET when a direct or related occupational crosswalk is available. For niche titles, we do not treat a broader SOC family as an exact job-title wage.
  2. Cost-of-living adjustment applied using the San Antonio index of 88 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs checked separately.
  3. Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rather than claimed as exact employer payroll data.
  4. Take-home pay calculated using 2026 federal tax brackets (10%-37%), TX state income tax of 0.0%, and FICA (Social Security 6.2% + Medicare 1.45%).
  5. Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.

Authoritative data sources:

Last reviewed: 2026. Salary data updated annually as new BLS releases become available. Physician Assistant salaries can vary significantly based on employer, sector (Military vs others in San Antonio), specific skill set (Clinical Examination, Diagnosis, Procedure Assistance), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.

Frequently Asked Questions

What is the average Physician Assistant salary in San Antonio, TX?
The median Physician Assistant salary in San Antonio, TX is $108,240 per year as of 2026. This is adjusted for the local cost of living index of 88. Entry-level Physician Assistants earn around $80,960, while senior-level professionals can earn $138,160 or more.
How much does a Physician Assistant take home in San Antonio after taxes?
A Physician Assistant earning the median salary of $108,240 in San Antonio, TX takes home approximately $84,977 per year ($7,081/month) after federal, state, and local taxes. The effective tax rate is 21.5%.
Is San Antonio a good city for Physician Assistants?
San Antonio, TX has a cost of living index of 88 (below national average). Physician Assistants here earn above the city median. The local unemployment rate is 3.5% and top industries include Military, Healthcare, Tourism.
What skills are needed for a Physician Assistant in San Antonio?
Key skills for Physician Assistants include Clinical Examination, Diagnosis, Procedure Assistance, EHR, Patient Education. Typical education requirement is Master's Degree. Valuable certifications include PANCE, NCCPA Certification.
How does Physician Assistant salary in San Antonio compare to the national average?
The national median Physician Assistant salary is $123,000. In San Antonio, the adjusted salary is $108,240, which is 12.0% lower than the national average, reflecting the local cost of living.
What job titles are similar to Physician Assistant in San Antonio?
Related search terms for Physician Assistant in San Antonio, TX include PA, Physician Associate, Medical Assistant. Use them as comparison terms, not always exact matches: licensing, employer type, seniority, public-sector rules, and whether the role is W-2, contractor, clinical, technical, management, or sales-focused can change the salary range.

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Frequently Asked Questions

What is the average Physician Assistant salary in San Antonio, TX?

The median Physician Assistant salary in San Antonio, TX is $108,240 per year as of 2026. This is adjusted for the local cost of living index of 88. Entry-level Physician Assistants earn around $80,960, while senior-level professionals can earn $138,160 or more.

How much does a Physician Assistant take home in San Antonio after taxes?

A Physician Assistant earning the median salary of $108,240 in San Antonio, TX takes home approximately $84,977 per year ($7,081/month) after federal, state, and local taxes. The effective tax rate is 21.5%.

Is San Antonio a good city for Physician Assistants?

San Antonio, TX has a cost of living index of 88 (below national average). Physician Assistants here earn above the city median. The local unemployment rate is 3.5% and top industries include Military, Healthcare, Tourism.

What skills are needed for a Physician Assistant in San Antonio?

Key skills for Physician Assistants include Clinical Examination, Diagnosis, Procedure Assistance, EHR, Patient Education. Typical education requirement is Master's Degree. Valuable certifications include PANCE, NCCPA Certification.

How does Physician Assistant salary in San Antonio compare to the national average?

The national median Physician Assistant salary is $123,000. In San Antonio, the adjusted salary is $108,240, which is 12.0% lower than the national average, reflecting the local cost of living.

What job titles are similar to Physician Assistant in San Antonio?

Related search terms for Physician Assistant in San Antonio, TX include PA, Physician Associate, Medical Assistant. Use them as comparison terms, not always exact matches: licensing, employer type, seniority, public-sector rules, and whether the role is W-2, contractor, clinical, technical, management, or sales-focused can change the salary range.