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Physician Assistant Salary in Chicago, IL: 2026

Physician Assistant salary data for Chicago, IL, adjusted for local cost of living. Entry-level to senior pay ranges, take-home pay calculator, and local job market insights.

The median Physician Assistant salary in Chicago, IL is $127,940 per year ($10,662/month, $61.51/hr). That is the BLS OEWS May 2025 median annual wage for Physician Assistants in the Chicago-Naperville-Elgin, IL-IN metropolitan area, which covers Chicago. Salario's cost-of-living model (index 107) would have estimated $145,392; the entry, senior and top tiers below are Salario estimates rescaled to the BLS median.

Also known as: PA, Physician Associate, Medical Assistant. The estimates on this page are used for these related job titles in Chicago, IL, although actual pay can differ by title and scope.

Entry Level
$96K
$46/hr
Median
$128K
$62/hr
Senior
$163K
$79/hr
Top Earner
$195K
$94/hr

Median: BLS OEWS May 2025, Physician Assistants (SOC 29-1071), Chicago-Naperville-Elgin, IL-IN MSA. Entry, senior and top earner are Salario estimates rescaled to the BLS median.

Physician Assistant Take-Home Pay in Chicago

Tax Breakdown (Median Salary)

Gross Annual$127,940
Federal Tax-$19,440
State Tax (4.9% eff.)-$6,333
FICA (SS + Medicare)-$9,787
Annual Take-Home$92,380
Monthly Take-Home$7,698

Living Cost Comparison

Median Rent$1,750/mo
Rent-to-Income Ratio16.4%
Median Home Price$320,000
Cost of Living Index107
City Median Salary (BLS metro, all jobs)$54,720
Physician Assistant vs City Median+$73,220

Physician Assistant Requirements

Education
Master's Degree
Experience
0-2 years
Job Growth
28.0% (2024-2034)

Key Skills

Clinical ExaminationDiagnosisProcedure AssistanceEHRPatient Education

Physician Assistant salary search terms in Chicago

People comparing Physician Assistant pay in Chicago, IL may use related job-title wording. Salario keeps the main estimate tied to the Physician Assistant role, then treats the terms below as comparison phrases that should be checked for licensing, employer type, seniority, and role scope.

PAPhysician AssociateMedical Assistant
Comparison pointHow to use it
Primary local answer$127,940 median salary, $95,700-$163,300 modeled range, and $92,380 estimated take-home pay in Chicago.
Title variantsPA, Physician Associate, Medical Assistant can point to similar searches, but some variants may represent a narrower specialty or a higher/lower seniority band.
Offer comparisonCompare base salary, hourly equivalent, take-home pay, certifications, local cost of living, and whether the job is employee, contractor, public-sector, commission-heavy, or management-level.

Chicago Job Market Overview

Chicago, Illinois has a population of 2,696,555 and an unemployment rate of 4.2%. The top industries are Finance, Technology, Healthcare. The local job growth rate is 1.5%, and the average commute time is 35minutes. These local figures come from Salario's city dataset; verify current values with BLS Local Area Unemployment Statistics and Census QuickFacts.

Salary Percentile Breakdown: Physician Assistant in Chicago

Based on Salario's cost-of-living-adjusted salary tiers for Physician Assistant in Chicago, IL, here is an estimated percentile breakdown:

PercentileAnnual SalaryHourly EquivalentCareer Stage
10th (lowest)$95,700$46/hrEntry-level, < 1 yr exp.
25th$111,820$54/hrJunior, 1-3 yrs exp.
50th (median)$127,940$62/hrMid-career, 0-2 years
75th$163,300$79/hrSenior, 5-10 yrs exp.
90th (top)$194,500$94/hrLead/Principal, 10+ yrs

P50 is the measured BLS OEWS May 2025 metro median; P10, P25, P75 and P90 are approximations, not measured local percentiles: they map to Salario's entry, senior and top tiers rescaled to the BLS median, with P25 interpolated halfway between entry and median. Top earners (P90) typically include managers, specialists with rare skills, or those at high-paying employers in Chicago's Finance sector.

5-Year Salary Trajectory

Salario's national dataset models approximately 15.0% salary growth for Physician Assistants over the past 5 years. That national assumption is applied to the Chicago estimate below; it is not a measured local trend, and it should be compared with cumulative CPI inflation before treating it as a real-terms gain:

5 Years Ago
$111,252
Adjusted for Chicago COL
Today (2026)
$127,940
+15.0% vs 5y ago
Projected 2031
$147,131
If growth continues

Year-over-year, an average Physician Assistant can expect a 14.3% annual increase moving from entry to senior level over 4 years in Chicago. Negotiation, certifications (PANCE, NCCPA Certification), and changing employers strategically can accelerate this trajectory.

Chicago vs National Average

The national median Physician Assistant salary is $135,880 (BLS OEWS May 2025, Physician Assistants). In the Chicago-Naperville-Elgin, IL-IN metro, the BLS median of $127,940 is 5.8% below the national figure. Chicago's cost of living index is 107 (higher than the national average of 100), so the wage premium and the cost premium do not necessarily cancel out.

For Physician Assistants, this means: rent typically consumes 22.7% of take-home pay (households spending >30% are considered affordable), and a median home in Chicago costs about 3.5× annual take-home. Homeownership is relatively attainable on this salary in Chicago.

Industry Context: Finance in Chicago

Chicago's economy is anchored by Finance, Technology, Healthcare, with 2,696,555 residents and an unemployment rate of 4.2% in Salario's city dataset. Pay for Physician Assistants can differ by sector, so compare Finance employers with other local employers. The local job growth rate in Salario's city dataset is 1.5%, and Salario's job dataset lists a 28.0% growth outlook for Physician Assistant roles; check the BLS Occupational Outlook Handbook for the official 2024-2034 projection for the closest matching occupation.

Methodology & Data Sources

How we calculate Physician Assistant salaries in Chicago, IL:

  1. Local median is the BLS OEWS May 2025 median annual wage for Physician Assistants (SOC 29-1071) in the Chicago-Naperville-Elgin, IL-IN metropolitan statistical area, retrieved from the BLS Public Data API on September 17, 2026. BLS reports by metro area, so this is a regional figure, not a Chicago-only wage.
  2. Cost-of-living adjustment is shown only for comparison ($145,392 modeled) using the Chicago index of 107 relative to the national baseline of 100, with local rent, home price, unemployment, and tax inputs stored separately in Salario's city dataset.
  3. Percentile distribution (P10-P90) estimated from the entry, median, senior, and top compensation tiers in the Salario salary model rescaled to the BLS metro median rather than claimed as exact employer payroll data.
  4. Take-home pay calculated using 2026 federal tax brackets (10%-37%), IL 2026 state income tax brackets after the standard deduction (top rate 5.0%), and FICA (Social Security 6.2% + Medicare 1.45%).
  5. Tax brackets and standard deduction ($16,100 single filer for tax year 2026) sourced from IRS Revenue Procedure 2025-32 and updated annually.

Authoritative data sources:

Last reviewed: 2026. Salario's salary dataset is refreshed periodically, not automatically; check the linked BLS releases for the latest official data. Physician Assistant salaries can vary significantly based on employer, sector (Finance vs others in Chicago), specific skill set (Clinical Examination, Diagnosis, Procedure Assistance), and individual negotiation. Always verify current compensation through multiple sources before making career decisions.

Frequently Asked Questions

What is the average Physician Assistant salary in Chicago, IL?
The median Physician Assistant salary in Chicago, IL is $127,940 per year: the BLS OEWS May 2025 median annual wage for Physician Assistants (SOC 29-1071) in the Chicago-Naperville-Elgin, IL-IN metropolitan area. BLS publishes wages by metro area, not by city. The entry-level estimate of around $95,700 and the senior estimate of $163,300 or more are Salario tiers calibrated to that BLS median, not BLS percentiles.
How much does a Physician Assistant take home in Chicago after taxes?
A Physician Assistant earning the median salary of $127,940 in Chicago, IL takes home approximately $92,380 per year ($7,698/month) after federal, state, and local taxes. The effective tax rate is 27.8%.
Is Chicago a good city for Physician Assistants?
Chicago, IL has a cost of living index of 107 (above national average). Physician Assistants here earn above the city median. The local unemployment rate is 4.2% and top industries include Finance, Technology, Healthcare.
What skills are needed for a Physician Assistant in Chicago?
Key skills for Physician Assistants include Clinical Examination, Diagnosis, Procedure Assistance, EHR, Patient Education. Typical education requirement is Master's Degree. Valuable certifications include PANCE, NCCPA Certification.
How does Physician Assistant salary in Chicago compare to the national average?
The national median for Physician Assistants is $135,880 (BLS OEWS May 2025). In the Chicago-Naperville-Elgin, IL-IN metro, the BLS median is $127,940, which is 5.8% lower than the national figure. For comparison, Salario's cost-of-living model (index 107) would have estimated $145,392.
What job titles are similar to Physician Assistant in Chicago?
Related search terms for Physician Assistant in Chicago, IL include PA, Physician Associate, Medical Assistant. Use them as comparison terms, not always exact matches: licensing, employer type, seniority, public-sector rules, and whether the role is W-2, contractor, clinical, technical, management, or sales-focused can change the salary range.

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Frequently Asked Questions

What is the average Physician Assistant salary in Chicago, IL?

The median Physician Assistant salary in Chicago, IL is $127,940 per year: the BLS OEWS May 2025 median annual wage for Physician Assistants (SOC 29-1071) in the Chicago-Naperville-Elgin, IL-IN metropolitan area. BLS publishes wages by metro area, not by city. The entry-level estimate of around $95,700 and the senior estimate of $163,300 or more are Salario tiers calibrated to that BLS median, not BLS percentiles.

How much does a Physician Assistant take home in Chicago after taxes?

A Physician Assistant earning the median salary of $127,940 in Chicago, IL takes home approximately $92,380 per year ($7,698/month) after federal, state, and local taxes. The effective tax rate is 27.8%.

Is Chicago a good city for Physician Assistants?

Chicago, IL has a cost of living index of 107 (above national average). Physician Assistants here earn above the city median. The local unemployment rate is 4.2% and top industries include Finance, Technology, Healthcare.

What skills are needed for a Physician Assistant in Chicago?

Key skills for Physician Assistants include Clinical Examination, Diagnosis, Procedure Assistance, EHR, Patient Education. Typical education requirement is Master's Degree. Valuable certifications include PANCE, NCCPA Certification.

How does Physician Assistant salary in Chicago compare to the national average?

The national median for Physician Assistants is $135,880 (BLS OEWS May 2025). In the Chicago-Naperville-Elgin, IL-IN metro, the BLS median is $127,940, which is 5.8% lower than the national figure. For comparison, Salario's cost-of-living model (index 107) would have estimated $145,392.

What job titles are similar to Physician Assistant in Chicago?

Related search terms for Physician Assistant in Chicago, IL include PA, Physician Associate, Medical Assistant. Use them as comparison terms, not always exact matches: licensing, employer type, seniority, public-sector rules, and whether the role is W-2, contractor, clinical, technical, management, or sales-focused can change the salary range.